Ethambutol Partitioning in Tuberculous Pulmonary Lesions Explains Its Clinical Efficacy

Clinical trials and practice have shown that ethambutol is an important component of the first-line tuberculosis (TB) regime. This contrasts the drug's rather modest potency and lack of activity against nongrowing persister mycobacteria. The standard plasma-based pharmacokinetic-pharmacodynamic...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Zimmerman, Matthew, Lestner, Jodi, Prideaux, Brendan, O'Brien, Paul, Dias-Freedman, Isabela, Chen, Chao, Dietzold, Jillian, Daudelin, Isaac, Kaya, Firat, Blanc, Landry, Chen, Pei-Yu, Park, Steven, Salgame, Padmini, Sarathy, Jansy, Dartois, Véronique
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571334/
https://ncbi.nlm.nih.gov/pubmed/28696241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00924-17
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