Persistent Loss of Hepatitis B Virus Markers in Serum without Cellular Immunity by Combination of Peginterferon and Entecavir Therapy in Humanized Mice

Nucleot(s)ide analogues and peginterferon (PEG-IFN) treatment are the only approved therapies for chronic hepatitis B virus (HBV) infection. However, complete eradication of the virus, as indicated by persistent loss of hepatitis B surface antigen (HBsAg), is rare among treated patients. This is due...

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Udgivet i:Antimicrob Agents Chemother
Main Authors: Uchida, Takuro, Imamura, Michio, Hayes, C. Nelson, Hiraga, Nobuhiko, Kan, Hiromi, Tsuge, Masataka, Abe-Chayama, Hiromi, Zhang, Yizhou, Makokha, Grace Naswa, Aikata, Hiroshi, Miki, Daiki, Ochi, Hidenori, Ishida, Yuji, Tateno, Chise, Chayama, Kazuaki
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2017
Fag:
Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571312/
https://ncbi.nlm.nih.gov/pubmed/28696237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00725-17
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