Exosomes from high glucose-treated glomerular endothelial cells trigger the epithelial-mesenchymal transition and dysfunction of podocytes

New data indicate that abnormal glomerular endothelial cell (GEC)-podocyte crosstalk plays a critical role in diabetic nephropathy (DN). The aim of our study is to investigate the role of exosomes from high glucose (HG)-treated GECs in the epithelial-mesenchymal transition (EMT) and dysfunction of p...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wu, Xiaoming, Gao, Yanbin, Xu, Liping, Dang, Wanyu, Yan, Huimin, Zou, Dawei, Zhu, Zhiyao, Luo, Liangtao, Tian, Nianxiu, Wang, Xiaolei, Tong, Yu, Han, Zheji
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571220/
https://ncbi.nlm.nih.gov/pubmed/28839221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09907-6
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