hnRNP A1 may interact simultaneously with telomeric DNA and the human telomerase RNA in vitro
The hnRNP A1 protein and a shortened derivative (UP1) promote telomere elongation in mammalian cells. In support of a direct role for A1 in telomere biogenesis, we have shown that the recombinant UP1 protein binds to telomeric DNA sequences in vitro, and pulls down telomerase activity from a cell ex...
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| Vydáno v: | Nucleic Acids Res |
|---|---|
| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2001
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55710/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11376145/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.11.2268 |
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