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hnRNP A1 may interact simultaneously with telomeric DNA and the human telomerase RNA in vitro

The hnRNP A1 protein and a shortened derivative (UP1) promote telomere elongation in mammalian cells. In support of a direct role for A1 in telomere biogenesis, we have shown that the recombinant UP1 protein binds to telomeric DNA sequences in vitro, and pulls down telomerase activity from a cell ex...

詳細記述

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書誌詳細
出版年:Nucleic Acids Res
主要な著者: Fiset, Stéphan, Chabot, Benoit
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2001
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55710/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11376145/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.11.2268
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