Polymyxin B containing polyion complex (PIC) nanoparticles: Improving the antimicrobial activity by tailoring the degree of polymerisation of the inert component

Here, we describe the preparation and characterisation of polyion complex (PIC) nanoparticles containing last resort antimicrobial polymyxin B (Pol-B). PIC nanoparticles were prepared with poly(styrene sulphonate) (PSS) as an inert component, across a range of degrees of polymerisation to evaluate t...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Insua, Ignacio, Zizmare, Laimdota, Peacock, Anna F. A., Krachler, Anne Marie, Fernandez-Trillo, Francisco
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570901/
https://ncbi.nlm.nih.gov/pubmed/28839223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09667-3
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