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Single Cell Methylomes Identify Neuronal Subtypes and Regulatory Elements in Mammalian Cortex
The mammalian brain contains diverse neuronal types, yet we lack single-cell epigenomic assays able to identify and characterize them. DNA methylation is a stable epigenetic mark that distinguishes cell types and marks regulatory elements. We generated >6,000 methylomes from single neuronal nucle...
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| Publicado no: | Science |
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| Main Authors: | , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5570439/ https://ncbi.nlm.nih.gov/pubmed/28798132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aan3351 |
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