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Allele-specific non-CG DNA methylation marks domains of active chromatin in female mouse brain

DNA methylation at gene promoters in a CG context is associated with transcriptional repression, including at genes silenced on the inactive X chromosome in females. Non-CG methylation (mCH) is a distinct feature of the neuronal epigenome that is differentially distributed between males and females...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Keown, Christopher L., Berletch, Joel B., Castanon, Rosa, Nery, Joseph R., Disteche, Christine M., Ecker, Joseph R., Mukamel, Eran A.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389278/
https://ncbi.nlm.nih.gov/pubmed/28320934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1611905114
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