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Mobile small RNAs regulate genome-wide DNA methylation

RNA silencing at the transcriptional and posttranscriptional levels regulates endogenous gene expression, controls invading transposable elements (TEs), and protects the cell against viruses. Key components of the mechanism are small RNAs (sRNAs) of 21–24 nt that guide the silencing machinery to the...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Lewsey, Mathew G., Hardcastle, Thomas J., Melnyk, Charles W., Molnar, Attila, Valli, Adrián, Urich, Mark A., Nery, Joseph R., Baulcombe, David C., Ecker, Joseph R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760824/
https://ncbi.nlm.nih.gov/pubmed/26787884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1515072113
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