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Mobile small RNAs regulate genome-wide DNA methylation

RNA silencing at the transcriptional and posttranscriptional levels regulates endogenous gene expression, controls invading transposable elements (TEs), and protects the cell against viruses. Key components of the mechanism are small RNAs (sRNAs) of 21–24 nt that guide the silencing machinery to the...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Lewsey, Mathew G., Hardcastle, Thomas J., Melnyk, Charles W., Molnar, Attila, Valli, Adrián, Urich, Mark A., Nery, Joseph R., Baulcombe, David C., Ecker, Joseph R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760824/
https://ncbi.nlm.nih.gov/pubmed/26787884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1515072113
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