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Frequent AKT1(E17K) mutations in skull base meningiomas are associated with mTOR and ERK1/2 activation and reduced time to tumor recurrence
BACKGROUND. Skull base meningiomas are considered to be difficult for surgical treatment. We wondered whether genetic alterations recently identified in benign non-NF2-mutated World Health Organization (WHO) grade I meningiomas are related to clinical features of skull base meningiomas and whether d...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5570238/ https://ncbi.nlm.nih.gov/pubmed/28482067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox018 |
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