Histologic and biochemical alterations predict pulmonary mechanical dysfunction in aging mice with chronic lung inflammation

Both aging and chronic inflammation produce complex structural and biochemical alterations to the lung known to impact work of breathing. Mice deficient in surfactant protein D (Sftpd) develop progressive age-related lung pathology characterized by tissue destruction/remodeling, accumulation of foam...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS Comput Biol
Main Authors: Massa, Christopher B., Groves, Angela M., Jaggernauth, Smita U., Laskin, Debra L., Gow, Andrew J.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2017
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570219/
https://ncbi.nlm.nih.gov/pubmed/28837561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005570
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