The internalization signal in the cytoplasmic tail of lysosomal acid phosphatase consists of the hexapeptide PGYRHV.

Lysosomal acid phosphatase (LAP) is rapidly internalized from the cell surface due to a tyrosine-containing internalization signal in its 19 amino acid cytoplasmic tail. Measuring the internalization of a series of LAP cytoplasmic tail truncation and substitution mutants revealed that the N-terminal...

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Detalles Bibliográficos
Publicado en:EMBO J
Autores principales: Lehmann, L E, Eberle, W, Krull, S, Prill, V, Schmidt, B, Sander, C, von Figura, K, Peters, C
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 1992
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC557013/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1425575/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1992.tb05539.x
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