Mms1 binds to G-rich regions in Saccharomyces cerevisiae and influences replication and genome stability

The regulation of replication is essential to preserve genome integrity. Mms1 is part of the E3 ubiquitin ligase complex that is linked to replication fork progression. By identifying Mms1 binding sites genome-wide in Saccharomyces cerevisiae we connected Mms1 function to genome integrity and replic...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Wanzek, Katharina, Schwindt, Eike, Capra, John A., Paeschke, Katrin
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Genome Integrity, Repair and Replication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570088/
https://ncbi.nlm.nih.gov/pubmed/28535251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx467
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