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Mms1 binds to G-rich regions in Saccharomyces cerevisiae and influences replication and genome stability

The regulation of replication is essential to preserve genome integrity. Mms1 is part of the E3 ubiquitin ligase complex that is linked to replication fork progression. By identifying Mms1 binding sites genome-wide in Saccharomyces cerevisiae we connected Mms1 function to genome integrity and replic...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Wanzek, Katharina, Schwindt, Eike, Capra, John A., Paeschke, Katrin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570088/
https://ncbi.nlm.nih.gov/pubmed/28535251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx467
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