Interlinked DNA nano-circles for measuring topoisomerase II activity at the level of single decatenation events

DNA nano-structures present appealing new means for monitoring different molecules. Here, we demonstrate the assembly and utilization of a surface-attached double-stranded DNA catenane composed of two intact interlinked DNA nano-circles for specific and sensitive measurements of the life essential t...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Kristoffersen, Emil L., Givskov, Asger, Jørgensen, Line A., Jensen, Pia W., W. Byl, Jo Ann, Osheroff, Neil, Andersen, Anni H., Stougaard, Magnus, Ho, Yi-Ping, Knudsen, Birgitta R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Molecular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570003/
https://ncbi.nlm.nih.gov/pubmed/28541438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx480
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