Full shut-off of Escherichia coli RNA-polymerase by T7 phage requires a small phage-encoded DNA-binding protein

Infection of Escherichia coli by the T7 phage leads to rapid and selective inhibition of the bacterial RNA polymerase (RNAP) by the 7 kDa T7 protein Gp2. We describe the identification and functional and structural characterisation of a novel 7 kDa T7 protein, Gp5.7, which adopts a winged helix-turn...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Tabib-Salazar, Aline, Liu, Bing, Shadrin, Andrey, Burchell, Lynn, Wang, Zhexin, Wang, Zhihao, Goren, Moran G., Yosef, Ido, Qimron, Udi, Severinov, Konstantin, Matthews, Steve J., Wigneshweraraj, Sivaramesh
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5569994/
https://ncbi.nlm.nih.gov/pubmed/28486695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx370
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