Pleiotropic Effects of Biguanides on Mitochondrial Reactive Oxygen Species Production

Metformin is widely prescribed as a first-choice antihyperglycemic drug for treatment of type 2 diabetes mellitus, and recent epidemiological studies showed its utility also in cancer therapy. Although it is in use since the 1970s, its molecular target, either for antihyperglycemic or antineoplastic...

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Bibliographic Details
Published in:Oxid Med Cell Longev
Main Authors: Pecinova, Alena, Drahota, Zdenek, Kovalcikova, Jana, Kovarova, Nikola, Pecina, Petr, Alan, Lukas, Zima, Michal, Houstek, Josef, Mracek, Tomas
Format: Artigo
Language:Inglês
Published: Hindawi 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5569935/
https://ncbi.nlm.nih.gov/pubmed/28874953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/7038603
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