Afatinib Activity in Platinum-Refractory Metastatic Urothelial Carcinoma in Patients With ERBB Alterations

PURPOSE: Somatic mutations and copy number variation in the ERBB family are frequent in urothelial carcinoma (UC) and may represent viable therapeutic targets. We studied whether afatinib (an oral, irreversible inhibitor of the ErbB family) has activity in UC and if specific ERBB molecular alteratio...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:J Clin Oncol
Hoofdauteurs: Choudhury, Noura J., Campanile, Alexa, Antic, Tatjana, Yap, Kai Lee, Fitzpatrick, Carrie A., Wade, James L., Karrison, Theodore, Stadler, Walter M., Nakamura, Yusuke, O’Donnell, Peter H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Clinical Oncology 2016
Onderwerpen:
ORIGINAL REPORTS
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5569685/
https://ncbi.nlm.nih.gov/pubmed/27044931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2015.66.3047
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items