Effect of Degarelix, a Gonadotropin-Releasing Hormone Receptor Antagonist for the Treatment of Prostate Cancer, on Cardiac Repolarisation in a Randomised, Placebo and Active Comparator Controlled Thorough QT/QTc Trial in Healthy Men

BACKGROUND AND OBJECTIVES: Degarelix is a gonadotropin-releasing hormone antagonist registered for the treatment of advanced hormone-dependent prostate cancer. Treatment causing androgen deprivation is associated with QT prolongation and this study investigated whether degarelix at supratherapeutic...

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Detalhes bibliográficos
Publicado no:Clin Drug Investig
Main Authors: Olsson, Håkan, Petri, Niclas, Erichsen, Lars, Malmberg, Anders, Grundemar, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2017
Assuntos:
Original Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5569649/
https://ncbi.nlm.nih.gov/pubmed/28660498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40261-017-0547-7
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