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Molecular cloning of human growth inhibitory factor cDNA and its down-regulation in Alzheimer's disease.

In previous studies, we discovered a growth inhibitory factor (GIF) that was abundant in normal human brain, but greatly reduced in Alzheimer's disease (AD) brain. Molecular cloning of a full-length cDNA for human GIF revealed that the GIF had striking homology to metallothioneins. Furthermore,...

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Autori principali: Tsuji, S, Kobayashi, H, Uchida, Y, Ihara, Y, Miyatake, T
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1992
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC556960/
https://ncbi.nlm.nih.gov/pubmed/1464312
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