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Dominant-negative mutants of a yeast G-protein beta subunit identify two functional regions involved in pheromone signalling.

The STE4 gene, which encodes the beta subunit of the mating response G-protein in the yeast Saccharomyces cerevisiae, was subjected to a saturation mutagenesis using 'doped' oligodeoxynucleotides. We employed a genetic screen to select dominant-negative STE4 mutants, which when overexpress...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Leberer, E, Dignard, D, Hougan, L, Thomas, D Y, Whiteway, M
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1992
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC556956/
https://ncbi.nlm.nih.gov/pubmed/1464310
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