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Granulocytic myeloid-derived suppressor cells suppress virus-specific CD8(+) T cell responses during acute Friend retrovirus infection

BACKGROUND: Myeloid-derived suppressor cells (MDSCs) can suppress T cell responses in several different diseases. Previously these suppressive cells were observed to expand in HIV patients and in a mouse retrovirus model, yet their suppressive effect on virus-specific CD8(+) T cells in vitro and in...

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Detalhes bibliográficos
Publicado no:Retrovirology
Main Authors: Drabczyk-Pluta, Malgorzata, Werner, Tanja, Hoffmann, Daniel, Leng, Qibin, Chen, Lieping, Dittmer, Ulf, Zelinskyy, Gennadiy
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5569525/
https://ncbi.nlm.nih.gov/pubmed/28835242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-017-0364-3
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