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The Level of Friend Retrovirus Replication Determines the Cytolytic Pathway of CD8(+) T-Cell-Mediated Pathogen Control

Cytotoxic T cells (CTL) play a central role in the control of viral infections. Their antiviral activity can be mediated by at least two cytotoxic pathways, namely, the granule exocytosis pathway, involving perforin and granzymes, and the Fas-FasL pathway. However, the viral factor(s) that influence...

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Detalhes bibliográficos
Main Authors: Zelinskyy, Gennadiy, Balkow, Sandra, Schimmer, Simone, Werner, Tanja, Simon, Markus M., Dittmer, Ulf
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168789/
https://ncbi.nlm.nih.gov/pubmed/17728236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01554-07
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