CD8(+) T-Cell Dysfunction due to Cytolytic Granule Deficiency in Persistent Friend Retrovirus Infection

Virus-specific CD8(+) T cells are critical for the control of acute Friend virus (FV) infections, but are rendered impotent by CD4(+) regulatory T cells during the chronic phase of infection. The current study examines this CD8(+) T-cell dysfunction by analyzing the production and release of cytolyt...

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Detalhes bibliográficos
Main Authors: Zelinskyy, Gennadiy, Robertson, Shelly J., Schimmer, Simone, Messer, Ronald J., Hasenkrug, Kim J., Dittmer, Ulf
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182617/
https://ncbi.nlm.nih.gov/pubmed/16051854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.16.10619-10626.2005
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