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iNOS promotes hypothalamic insulin resistance associated with deregulation of energy balance and obesity in rodents

Inducible nitric oxide (iNOS)-mediated S-nitrosation of the metabolic signaling pathway has emerged as a post-translational modification that triggers insulin resistance in obesity and aging. However, the effects of S-nitrosation in controlling energy homeostasis are unknown. Thus, in the present st...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Katashima, Carlos Kiyoshi, Silva, Vagner Ramon Rodrigues, Lenhare, Luciene, Marin, Rodrigo Miguel, Carvalheira, José Barreto Campello
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5569114/
https://ncbi.nlm.nih.gov/pubmed/28835706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08920-z
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