Development of a versatile and conventional technique for gene disruption in filamentous fungi based on CRISPR-Cas9 technology

Filamentous fungi represent an invaluable source of pharmaceutically active compounds. The development of versatile methods to genetically manipulate filamentous fungi is of great value for improving the low yields of bioactive metabolites and expanding chemical diversity. The CRISPR-Cas9-based syst...

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發表在:Sci Rep
Main Authors: Zheng, Yan-Mei, Lin, Fu-Long, Gao, Hao, Zou, Gen, Zhang, Jiang-Wei, Wang, Gao-Qian, Chen, Guo-Dong, Zhou, Zhi-Hua, Yao, Xin-Sheng, Hu, Dan
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2017
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5569088/
https://ncbi.nlm.nih.gov/pubmed/28835711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10052-3
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