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Cutaneous pigmentation modulates skin sensitivity via tyrosinase-dependent dopaminergic signalling

We propose a new mechanism of sensory modulation through cutaneous dopaminergic signalling. We hypothesize that dopaminergic signalling contributes to differential cutaneous sensitivity in darker versus lighter pigmented humans and mouse strains. We show that thermal and mechanical cutaneous sensiti...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Ono, Kentaro, Viet, Chi T., Ye, Yi, Dang, Dongmin, Hitomi, Suzuro, Toyono, Takashi, Inenaga, Kiyotoshi, Dolan, John C., Schmidt, Brian L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5569050/
https://ncbi.nlm.nih.gov/pubmed/28835637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09682-4
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