Brain microvascular injury and white matter disease provoked by diabetes-associated hyperamylinemia

OBJECTIVES: The brain blood vessels of patients with type-2 diabetes and dementia have deposition of amylin, an amyloidogenic hormone co-secreted with insulin. It is not known whether vascular amylin deposition is a consequence or a trigger of vascular injury. We tested the hypothesis that the vascu...

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Detaylı Bibliyografya
Yayımlandı:Ann Neurol
Asıl Yazarlar: Ly, Han, Verma, Nirmal, Wu, Fengen, Liu, Miao, Saatman, Kathryn E., Nelson, Peter T., Slevin, John T., Goldstein, Larry B., Biessels, Geert Jan, Despa, Florin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568970/
https://ncbi.nlm.nih.gov/pubmed/28696548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24992
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