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Conditional abrogation of Transforming Growth Factor Beta Receptor 1 in PTEN-inactivated endometrium promotes endometrial cancer progression in mice

Although a putative role for TGF beta (TGFB) signaling in the pathogenesis of human endometrial cancer has long been proposed, the precise function of TGFB signaling in the development and progression of endometrial cancer remains elusive. Depletion of PTEN in the mouse uterus causes endometrial can...

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Detalhes bibliográficos
Publicado no:J Pathol
Main Authors: Gao, Yang, Lin, Pengfei, Lydon, John P., Li, Qinglei
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568928/
https://ncbi.nlm.nih.gov/pubmed/28657664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4930
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