Andexanet Alfa for Acute Major Bleeding Associated with Factor Xa Inhibitors

BACKGROUND: Andexanet alfa (andexanet) is a recombinant modified human factor Xa decoy protein that has been shown to reverse the inhibition of factor Xa in healthy volunteers. METHODS: In this multicenter, prospective, open-label, single-group study, we evaluated 67 patients who had acute major ble...

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Detaylı Bibliyografya
Yayımlandı:N Engl J Med
Asıl Yazarlar: Connolly, Stuart J., Milling, Truman J., Eikelboom, John W., Gibson, C. Michael, Curnutte, John T., Gold, Alex, Bronson, Michele D., Lu, Genmin, Conley, Pamela B., Verhamme, Peter, Schmidt, Jeannot, Middeldorp, Saskia, Cohen, Alexander T., Beyer-Westendorf, Jan, Albaladejo, Pierre, Lopez-Sendon, Jose, Goodman, Shelly, Leeds, Janet, Wiens, Brian L., Siegal, Deborah M., Zotova, Elena, Meeks, Brandi, Nakamya, Juliet, Lim, W. Ting, Crowther, Mark
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568772/
https://ncbi.nlm.nih.gov/pubmed/27573206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1607887
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