Andexanet Alfa for Acute Major Bleeding Associated with Factor Xa Inhibitors

BACKGROUND: Andexanet alfa (andexanet) is a recombinant modified human factor Xa decoy protein that has been shown to reverse the inhibition of factor Xa in healthy volunteers. METHODS: In this multicenter, prospective, open-label, single-group study, we evaluated 67 patients who had acute major ble...

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書誌詳細
出版年:N Engl J Med
主要な著者: Connolly, Stuart J., Milling, Truman J., Eikelboom, John W., Gibson, C. Michael, Curnutte, John T., Gold, Alex, Bronson, Michele D., Lu, Genmin, Conley, Pamela B., Verhamme, Peter, Schmidt, Jeannot, Middeldorp, Saskia, Cohen, Alexander T., Beyer-Westendorf, Jan, Albaladejo, Pierre, Lopez-Sendon, Jose, Goodman, Shelly, Leeds, Janet, Wiens, Brian L., Siegal, Deborah M., Zotova, Elena, Meeks, Brandi, Nakamya, Juliet, Lim, W. Ting, Crowther, Mark
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568772/
https://ncbi.nlm.nih.gov/pubmed/27573206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1607887
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