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SREBP1 contributes to resolution of pro-inflammatory TLR4 signaling by reprogramming fatty acid metabolism

Macrophages play pivotal roles in both the induction and resolution phases of inflammatory processes. Macrophages have been shown to synthesize anti-inflammatory fatty acids in an LXR-dependent manner, but whether the production of these species contributes to the resolution phase of inflammatory re...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Oishi, Yumiko, Spann, Nathanael J., Link, Verena M., Muse, Evan D., Strid, Tobias, Edillor, Chantle, Kolar, Matthew J., Matsuzaka, Takashi, Hayakawa, Sumio, Tao, Jenhan, Kaikkonen, Minna U., Carlin, Aaron F., Lam, Michael T., Manabe, Ichiro, Shimano, Hitoshi, Saghatelian, Alan, Glass, Christopher K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568699/
https://ncbi.nlm.nih.gov/pubmed/28041958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.11.009
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