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Bicarbonate alters cellular responses in respiration assays

Metabolic assay buffers often omit bicarbonate, which is susceptible to alkalinisation in an open environment. Here, we assessed the effect of including bicarbonate in respirometry experiments. By supplementing HEPES-buffered media with low concentrations of bicarbonate, we found increased respirati...

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Détails bibliographiques
Publié dans:Biochem Biophys Res Commun
Auteurs principaux: Krycer, James R., Fisher-Wellman, Kelsey H., Fazakerley, Daniel J., Muoio, Deborah M., James, David E.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568524/
https://ncbi.nlm.nih.gov/pubmed/28559140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2017.05.151
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