Versican-derived matrikines regulate Batf3-dendritic cell differentiation and promote T-cell infiltration in colorectal cancer

Colorectal cancer (CRC) originates within immunologically complex microenvironments. To date the benefits of immunotherapy have been modest except in neoantigen-laden mismatch repair (MMR)-deficient tumors. Approaches to enhance tumor-infiltrating lymphocytes in the tumor bed may substantially augme...

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Опубликовано в: :J Immunol
Главные авторы: Hope, Chelsea, Emmerich, Philip B., Papadas, Athanasios, Pagenkopf, Adam, Matkowskyj, Kristina A., Van De Hey, Dana R., Payne, Susan N., Clipson, Linda, Callander, Natalie S., Hematti, Peiman, Miyamoto, Shigeki, Johnson, Michael G., Deming, Dustin A., Asimakopoulos, Fotis
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568487/
https://ncbi.nlm.nih.gov/pubmed/28754680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700529
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