Versican-derived matrikines regulate Batf3-dendritic cell differentiation and promote T-cell infiltration in colorectal cancer

Colorectal cancer (CRC) originates within immunologically complex microenvironments. To date the benefits of immunotherapy have been modest except in neoantigen-laden mismatch repair (MMR)-deficient tumors. Approaches to enhance tumor-infiltrating lymphocytes in the tumor bed may substantially augme...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Hope, Chelsea, Emmerich, Philip B., Papadas, Athanasios, Pagenkopf, Adam, Matkowskyj, Kristina A., Van De Hey, Dana R., Payne, Susan N., Clipson, Linda, Callander, Natalie S., Hematti, Peiman, Miyamoto, Shigeki, Johnson, Michael G., Deming, Dustin A., Asimakopoulos, Fotis
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568487/
https://ncbi.nlm.nih.gov/pubmed/28754680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700529
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