Versican-derived matrikines regulate Batf3-dendritic cell differentiation and promote T-cell infiltration in colorectal cancer

Colorectal cancer (CRC) originates within immunologically complex microenvironments. To date the benefits of immunotherapy have been modest except in neoantigen-laden mismatch repair (MMR)-deficient tumors. Approaches to enhance tumor-infiltrating lymphocytes in the tumor bed may substantially augme...

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Gepubliceerd in:J Immunol
Hoofdauteurs: Hope, Chelsea, Emmerich, Philip B., Papadas, Athanasios, Pagenkopf, Adam, Matkowskyj, Kristina A., Van De Hey, Dana R., Payne, Susan N., Clipson, Linda, Callander, Natalie S., Hematti, Peiman, Miyamoto, Shigeki, Johnson, Michael G., Deming, Dustin A., Asimakopoulos, Fotis
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568487/
https://ncbi.nlm.nih.gov/pubmed/28754680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700529
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