Versican-derived matrikines regulate Batf3-dendritic cell differentiation and promote T-cell infiltration in colorectal cancer

Colorectal cancer (CRC) originates within immunologically complex microenvironments. To date the benefits of immunotherapy have been modest except in neoantigen-laden mismatch repair (MMR)-deficient tumors. Approaches to enhance tumor-infiltrating lymphocytes in the tumor bed may substantially augme...

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Udgivet i:J Immunol
Main Authors: Hope, Chelsea, Emmerich, Philip B., Papadas, Athanasios, Pagenkopf, Adam, Matkowskyj, Kristina A., Van De Hey, Dana R., Payne, Susan N., Clipson, Linda, Callander, Natalie S., Hematti, Peiman, Miyamoto, Shigeki, Johnson, Michael G., Deming, Dustin A., Asimakopoulos, Fotis
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568487/
https://ncbi.nlm.nih.gov/pubmed/28754680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700529
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