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DNA transcription and repressor binding affect deletion formation in Escherichia coli plasmids.

Chimeric plasmids containing phage M13 and plasmid pBR322 sequences undergo deletions in Escherichia coli with a high frequency. In all plasmids one deletion endpoint is the M13 replication origin nick site. We examined the effects of transcription on the position of the other deletion end-point, by...

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Autori principali: Vilette, D, Uzest, M, Ehrlich, S D, Michel, B
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1992
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC556822/
https://ncbi.nlm.nih.gov/pubmed/1396563
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