Multimodal Lentiviral Vectors for Pharmacologically Controlled Switching Between Constitutive Single Gene Expression and Tetracycline-Regulated Multiple Gene Collaboration

Multimodal lentiviral vectors (LVs) allow switching between constitutive and tetracycline-regulated gene co-expressions in genetically modified cells. Transduction of murine primary hematopoietic progenitor cells (HPCs) with multimodal LVs in the absence of doxycycline ensures the constitutive expre...

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Udgivet i:Hum Gene Ther Methods
Main Authors: Stahlhut, Maike, Schambach, Axel, Kustikova, Olga S.
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc., publishers 2017
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Protocol
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568180/
https://ncbi.nlm.nih.gov/pubmed/28683573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2017.073
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