A Guide to Approaching Regulatory Considerations for Lentiviral-Mediated Gene Therapies

Lentiviral vectors are increasingly the gene transfer tool of choice for gene or cell therapies, with multiple clinical investigations showing promise for this viral vector in terms of both safety and efficacy. The third-generation vector system is well characterized, effectively delivers genetic ma...

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Bibliographic Details
Published in:Hum Gene Ther Methods
Main Authors: White, Michael, Whittaker, Roger, Gándara, Carolina, Stoll, Elizabeth A.
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2017
Subjects:
Special Issue on Lentiviral Vectors:Production, Engineering, and Application—Part 1Review Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568014/
https://ncbi.nlm.nih.gov/pubmed/28817344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2017.096
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