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MicroRNA-206 prevents hepatosteatosis and hyperglycemia by facilitating insulin signaling and impairing lipogenesis

BACKGROUND & AIMS: The paradox of selective hepatic insulin resistance, wherein the insulin-resistant liver fails to suppress glucose production but continues to produce lipids, has been central to the pathophysiology of hepatosteatosis and hyperglycemia. Our study was designed to investigate th...

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Detalhes bibliográficos
Publicado no:J Hepatol
Main Authors: Wu, Heng, Zhang, Tianpeng, Pan, Fei, Steer, Clifford J., Li, Zhuoyu, Chen, Xin, Song, Guisheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568011/
https://ncbi.nlm.nih.gov/pubmed/28025059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2016.12.016
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