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LXRα Promotes Hepatosteatosis in Part Through Activation of MicroRNA‐378 Transcription and Inhibition of Ppargc1β Expression

Nonalcoholic fatty liver disease (NAFLD) is a major risk factor of many end‐stage liver diseases. Alterations in microRNA expression have been reported in patients with NAFLD. However, the transcriptional mechanism(s) of dysregulated microRNAs under the state of NAFLD is poorly described, and microR...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Zhang, Tianpeng, Duan, Jiangyan, Zhang, Lei, Li, Zhuoyu, Steer, Clifford J., Yan, Guiqin, Song, Guisheng
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6519356/
https://ncbi.nlm.nih.gov/pubmed/30281809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30301
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