Activation of mammalian DNA ligase I through phosphorylation by casein kinase II.

Mammalian DNA ligase I has been shown to be a phosphoprotein. Dephosphorylation of purified DNA ligase I causes inactivation, an effect dependent on the presence of the N-terminal region of the protein. Expression of full-length human DNA ligase I in Escherichia coli yielded soluble but catalyticall...

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Bibliografiske detaljer
Main Authors: Prigent, C, Lasko, D D, Kodama, K, Woodgett, J R, Lindahl, T
Format: Artigo
Sprog:Inglês
Udgivet: 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC556774/
https://ncbi.nlm.nih.gov/pubmed/1639065
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