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NKG2D signaling enhances Natural Killer cell responses but alone is insufficient to drive expansion during mouse cytomegalovirus infection
Natural killer (NK) cells play a critical role in host defense against viruses. Here, we investigated the role of NKG2D in the expansion of NK cells after mouse cytomegalovirus (MCMV) infection. Wild-type and NKG2D-deficient (Klrk1(−/−)) Ly49H(+) NK cells robustly proliferated when infected with MCM...
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| Udgivet i: | J Immunol |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5567695/ https://ncbi.nlm.nih.gov/pubmed/28760883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700799 |
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