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Spontaneous Membrane Translocating Peptides: The Role of Leucine-Arginine Consensus Motifs

We previously used an orthogonal high-throughput screen to select peptides that spontaneously cross synthetic lipid bilayers without bilayer disruption. Many of the 12-residue spontaneous membrane translocating peptides (SMTPs) selected from the library contained a 5-residue consensus motif, LRLLR i...

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Bibliografiske detaljer
Udgivet i:Biophys J
Main Authors: Fuselier, Taylor, Wimley, William C.
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567601/
https://ncbi.nlm.nih.gov/pubmed/28834720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.06.070
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