Conversion of OprO into an OprP-like Channel by Exchanging Key Residues in the Channel Constriction

Under phosphate-limiting conditions, the channels OprP and OprO are induced and expressed in the outer membrane of Pseudomonas aeruginosa. Despite their large homology, the phosphate-specific OprP and the diphosphate-specific OprO pores show structural differences in their binding sites situated in...

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Bibliografiske detaljer
Udgivet i:Biophys J
Main Authors: Ganguly, Sonalli, Kesireddy, Anusha, Bárcena-Uribarri, Iván, Kleinekathöfer, Ulrich, Benz, Roland
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2017
Fag:
Channels and Transporters
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567594/
https://ncbi.nlm.nih.gov/pubmed/28834719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.07.004
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