Motor impairment and compensation in a hemiparkinsonian rat model: correlation between dopamine depletion severity, cerebral metabolism and gait patterns

BACKGROUND: In Parkinson’s disease (PD), cerebral dopamine depletion is associated with PD subtype-specific metabolic patterns of hypo- and hypermetabolism. It has been hypothesised that hypometabolism reflects impairment, while hypermetabolism may indicate compensatory activity. In order to associa...

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Detalhes bibliográficos
Publicado no:EJNMMI Res
Main Authors: Kordys, Elena, Apetz, Nadine, Schneider, Katharina, Duncan, Eilidh, Büschbell, Beatriz, Rohleder, Cathrin, Sué, Michael, Drzezga, Alexander, Neumaier, Bernd, Timmermann, Lars, Endepols, Heike
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567589/
https://ncbi.nlm.nih.gov/pubmed/28831764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-017-0317-9
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