Genomic correlates of glatiramer acetate adverse cardiovascular effects lead to a novel locus mediating coronary risk

Glatiramer acetate is used therapeutically in multiple sclerosis but also known for adverse effects including elevated coronary artery disease (CAD) risk. The mechanisms underlying the cardiovascular side effects of the medication are unclear. Here, we made use of the chromosomal variation in the ge...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Brænne, Ingrid, Zeng, Lingyao, Willenborg, Christina, Tragante, Vinicius, Kessler, Thorsten, Willer, Cristen J., Laakso, Markku, Wallentin, Lars, Franks, Paul W., Salomaa, Veikko, Dehghan, Abbas, Meitinger, Thomas, Samani, Nilesh J., Asselbergs, Folkert W., Erdmann, Jeanette, Schunkert, Heribert
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567477/
https://ncbi.nlm.nih.gov/pubmed/28829817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182999
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