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Discrimination of three types of homopolymers in single-stranded DNA with solid-state nanopores through external control of the DNA motion

To achieve DNA sequencing with solid-state nanopores, the speed of the DNA in the nanopore must be controlled to obtain sequence-specific signals. In this study, we fabricated a nanopore-sensing system equipped with a DNA motion controller. DNA strands were immobilized on a Si probe, and approach of...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Akahori, Rena, Yanagi, Itaru, Goto, Yusuke, Harada, Kunio, Yokoi, Takahide, Takeda, Ken-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567245/
https://ncbi.nlm.nih.gov/pubmed/28831056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08290-6
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